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Modeling of the Human Rhinovirus C Capsid Suggests a Novel Topography with Insights on Receptor Preference and Immunogenicity

Features of human rhinovirus (RV)-C virions that allow them to use novel cell receptors and evade immune responses are unknown. Unlike the RV-A+B, these isolates cannot be propagated in typical culture systems or grown for structure studies. Comparative sequencing, I-TASSER, MODELLER, ROBETTA, and r...

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Autors principals: Basta, Holly A., Sgro, Jean-Yves, Palmenberg, Ann C.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857591/
https://ncbi.nlm.nih.gov/pubmed/24314648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.10.006
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