Non-invasive imaging of infection after treatment with tumor-homing bacteria using chemical exchange saturation transfer (CEST) MRI

PURPOSE: To develop a non-invasive MRI method for determining the germination and infection of tumor-homing bacteria in bacteriolytic cancer therapy using endogenous CEST contrast. METHODS: The CEST parameters of the anaerobic gram-positive bacterium Clostridium novyi-NT (C. novyi-NT) were first cha...

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Autori principali: Liu, Guanshu, Bettegowda, Chetan, Qiao, Yuan, Staedtke, Verena, Chan, Kannie W.Y., Bai, Renyuan, Li, Yuguo, Riggins, Gregory J., Kinzler, Kenneth W., Bulte, Jeff W.M., McMahon, Michael T., Gilad, Assaf A., Vogelstein, Bert, Zhou, Shibin, van Zijl, Peter C.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857583/
https://ncbi.nlm.nih.gov/pubmed/24123389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24955
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