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Loss of centrioles causes chromosomal instability in vertebrate somatic cells

Most animal cells contain a centrosome, which comprises a pair of centrioles surrounded by an ordered pericentriolar matrix (PCM). Although the role of this organelle in organizing the mitotic spindle poles is well established, its precise contribution to cell division and cell survival remains a su...

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Détails bibliographiques
Auteurs principaux: Sir, Joo-Hee, Pütz, Monika, Daly, Owen, Morrison, Ciaran G., Dunning, Mark, Kilmartin, John V., Gergely, Fanni
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857480/
https://ncbi.nlm.nih.gov/pubmed/24297747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201309038
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