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Loss of centrioles causes chromosomal instability in vertebrate somatic cells

Most animal cells contain a centrosome, which comprises a pair of centrioles surrounded by an ordered pericentriolar matrix (PCM). Although the role of this organelle in organizing the mitotic spindle poles is well established, its precise contribution to cell division and cell survival remains a su...

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Detalhes bibliográficos
Main Authors: Sir, Joo-Hee, Pütz, Monika, Daly, Owen, Morrison, Ciaran G., Dunning, Mark, Kilmartin, John V., Gergely, Fanni
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857480/
https://ncbi.nlm.nih.gov/pubmed/24297747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201309038
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