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Loss of centrioles causes chromosomal instability in vertebrate somatic cells

Most animal cells contain a centrosome, which comprises a pair of centrioles surrounded by an ordered pericentriolar matrix (PCM). Although the role of this organelle in organizing the mitotic spindle poles is well established, its precise contribution to cell division and cell survival remains a su...

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Autores principales: Sir, Joo-Hee, Pütz, Monika, Daly, Owen, Morrison, Ciaran G., Dunning, Mark, Kilmartin, John V., Gergely, Fanni
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857480/
https://ncbi.nlm.nih.gov/pubmed/24297747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201309038
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