Molecular Evidence for a Thymus-Independent Partial T Cell Development in a FOXN1(−/−) Athymic Human Fetus

The thymus is the primary organ able to support T cell ontogeny, abrogated in FOXN1(−/−) human athymia. Although evidence indicates that in animal models T lymphocytes may differentiate at extrathymic sites, whether this process is really thymus-independent has still to be clarified. In an athymic F...

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Detalhes bibliográficos
Main Authors: Fusco, Anna, Panico, Luigi, Gorrese, Marisa, Bianchino, Gabriella, Barone, Maria V., Grieco, Vitina, Vitiello, Laura, D’Assante, Roberta, Romano, Rosa, Palamaro, Loredana, Scalia, Giulia, Vecchio, Luigi Del, Pignata, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857207/
https://ncbi.nlm.nih.gov/pubmed/24349129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081786
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