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Fluctuation Analysis: Can Estimates Be Trusted?
The estimation of mutation rates and relative fitnesses in fluctuation analysis is based on the unrealistic hypothesis that the single-cell times to division are exponentially distributed. Using the classical Luria-Delbrück distribution outside its modelling hypotheses induces an important bias on t...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857183/ https://ncbi.nlm.nih.gov/pubmed/24349026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080958 |
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