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Aldose reductase inhibitor counteracts the enhanced expression of matrix metalloproteinase-10 and improves corneal wound healing in galactose-fed rats

PURPOSE: We investigated the effect of an aldose reductase inhibitor (ARI) and the role of matrix metalloproteinase (MMP)-10 on recovery after corneal epithelium removal in a rat diabetic keratopathy model. METHODS: Three-week-old Sprague-Dawley rats were fed the following diets for 6 weeks: normal...

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Autors principals: Takamura, Yoshihiro, Matsumoto, Takafumi, Tomomatsu, Takeshi, Matsumura, Takehiro, Takihara, Yuji, Inatani, Masaru
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857161/
https://ncbi.nlm.nih.gov/pubmed/24339723
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