Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors

Photodynamic diagnosis (PDD) is a practical tool currently used in surgical operation of aggressive brain tumors, such as glioblastoma. PDD is achieved by a photon-induced physicochemical reaction which is induced by excitation of protoporphyrin IX (PpIX) exposed to light. Fluorescence-guided gross-...

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Main Authors: Ishikawa, Toshihisa, Takahashi, Kenkichi, Ikeda, Naokado, Kajimoto, Yoshinaga, Hagiya, Yuichiro, Ogura, Shun-ichiro, Miyatake, Shin-ichi, Kuroiwa, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2011
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857086/
https://ncbi.nlm.nih.gov/pubmed/24310600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics3030615
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