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Blinatumomab induces autologous T-cell killing of chronic lymphocytic leukemia cells
Chronic lymphocytic leukemia is an incurable B-cell malignancy that is associated with tumor cell-mediated T-cell dysfunction. It therefore represents a challenging disease for T-cell immunotherapeutics. The CD19/CD3 bi-specific antibody construct blinatumomab (AMG103 or MT103) has been tested clini...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Ferrata Storti Foundation
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857012/ https://ncbi.nlm.nih.gov/pubmed/23812940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082248 |
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