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Urinary Desmosine: A Biomarker of Structural Lung Injury during CF Pulmonary Exacerbation

RATIONALE: Cystic fibrosis (CF) lung disease is characterized by structural changes and remodeling in airway architecture and lung parenchyma. Neutrophilic inflammation and infection lead to injury and breakdown of airway matrix constituents, including elastin. The non-invasive measurement of urinar...

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Detalhes bibliográficos
Main Authors: Laguna, Theresa A., Wagner, Brandie D., Starcher, Barry, Luckey Tarro, Heidi K., Mann, Shelley A., Sagel, Scott D., Accurso, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856884/
https://ncbi.nlm.nih.gov/pubmed/22431382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ppul.22525
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