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Transcription-factor binding and sliding on DNA studied using micro- and macroscopic models
Transcription factors search for specific operator sequences by alternating rounds of 3D diffusion with rounds of 1D diffusion (sliding) along the DNA. The details of such sliding have largely been beyond direct experimental observation. For this purpose we devised an analytical formulation of umbre...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856812/ https://ncbi.nlm.nih.gov/pubmed/24222688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307905110 |
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