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HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance dependent and independent populations

It has been postulated that drugs of abuse act synergistically with HIV, leading to increased neurotoxicity and neurocognitive impairment. The CNS impacts of HIV and drug use converge on the mesocorticolimbic dopamine (DA) system, which contains two main receptor subtypes: dopamine receptor 1 and 2....

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Detalhes bibliográficos
Main Authors: Jacobs, Michelle M., Murray, Jacinta, Byrd, Desiree A., Hurd, Yasmin L., Morgello, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856629/
https://ncbi.nlm.nih.gov/pubmed/24078558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-013-0204-8
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