Interaction of FKBP5 Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study

OBJECTIVE: The binding protein FKBP5 is an important modulator of the function of the glucocorticoid receptor, the main receptor of the stress horm one system. This turns the FKBP5 gene into a key candidate for gene-environment interactions, which are considered critical for pathogenesis of stress-r...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zimmermann, Petra, Brückl, Tanja, Nocon, Agnes, Pfister, Hildegard, Binder, Elisabeth B., Uhr, Manfred, Lieb, Roselind, Moffitt, Terrie E., Caspi, Avshalom, Holsboer, Florian, Ising, Marcus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856576/
https://ncbi.nlm.nih.gov/pubmed/21865530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2011.10111577
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