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Protein Ser/Thr phosphatase-6 is required for maintenance of E-cadherin at adherens junctions

BACKGROUND: Epithelial tissues depend on intercellular homodimerization of E-cadherin and loss of E-cadherin is central to the epithelial to mesenchymal transition seen in multiple human diseases. Signaling pathways regulate E-cadherin function and cellular distribution via phosphorylation of the cy...

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Detalhes bibliográficos
Main Authors: Ohama, Takashi, Wang, Lifu, Griner, Erin M, Brautigan, David L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856536/
https://ncbi.nlm.nih.gov/pubmed/24063632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-14-42
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