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Astrocyte elevated gene-1 is associated with metastasis in head and neck squamous cell carcinoma through p65 phosphorylation and upregulation of MMP1

BACKGROUND: The survival rate of head and neck squamous cell carcinoma (HNSCC) at advanced stage is poor, despite contemporary advances in treatment modalities. Recent studies have indicated that astrocyte elevated gene-1 (AEG-1), a single transmembrane protein without any known functional domains,...

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Bibliografiske detaljer
Main Authors: Wang, Yi-Ping, Liu, I-Ju, Chiang, Chiung-Pin, Wu, Han-Chung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856534/
https://ncbi.nlm.nih.gov/pubmed/24063540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-109
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