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Detection of Lymph Node Metastases in Human Colorectal Cancer by Using 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence with Spectral Unmixing

Accurate evaluation of metastatic lymph nodes (LNs) is indispensable for adequate treatment of colorectal cancer (CRC) patients. Here, we demonstrate detection of metastases of human CRC in removed fresh LNs using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence. A spectral...

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Detalhes bibliográficos
Main Authors: Harada, Kenichi, Harada, Yoshinori, Beika, Masatomo, Koizumi, Noriaki, Inoue, Koji, Murayama, Yasutoshi, Kuriu, Yoshiaki, Nakanishi, Masayoshi, Minamikawa, Takeo, Yamaoka, Yoshihisa, Dai, Ping, Yanagisawa, Akio, Otsuji, Eigo, Takamatsu, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856110/
https://ncbi.nlm.nih.gov/pubmed/24284403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141123140
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