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Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast

We demonstrate the use of a simple microfluidic setup, in which single budding yeast cells can be tracked throughout their entire lifespan. The microfluidic chip exploits the size difference between mother and daughter cells using an array of micropads. Upon loading, cells are trapped underneath the...

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Autori principali: Huberts, Daphne H. E. W., Janssens, Georges E., Lee, Sung Sik, Vizcarra, Ima Avalos, Heinemann, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855928/
https://ncbi.nlm.nih.gov/pubmed/23995364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50143
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