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Isoangustone A, a novel licorice compound, inhibits cell proliferation by targeting PI3-K, MKK4 and MKK7 in human melanoma

Licorice root is known to possess various bioactivities, including anti-inflammatory and anticancer effects. Glycyrrhizin (Gc), a triterpene compound, is the most abundant constituent of dried licorice root. However, high intake or long-term consumption of Gc causes several side effects, such as hyp...

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Detalhes bibliográficos
Main Authors: Song, Nu Ry, Lee, Eunjung, Byun, Sanguine, Kim, Jong-Eun, Mottamal, Madhusoodanan, Park, Jung Han Yoon, Lim, Soon Sung, Bode, Ann M., Lee, Hyong Joo, Lee, Ki Won, Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855899/
https://ncbi.nlm.nih.gov/pubmed/24104352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0134
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