Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis

In Mycobacterium tuberculosis, the protein MbtN (Rv1346) catalyzes the formation of a double bond in the fatty-acyl moiety of the siderophore mycobactin, which is used by this organism to acquire essential iron. MbtN is homologous to acyl-CoA dehydrogenases, whose general role is to catalyze the α,β...

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Autores principales: Chai, Ai-Fen, Johnston, Jodie M., Bunker, Richard D., Bulloch, Esther M. M., Evans, Genevieve L., Lott, J. Shaun, Baker, Edward N.
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2013
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855718/
https://ncbi.nlm.nih.gov/pubmed/24316828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113027000
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