Alternative Activation of Macrophages and Induction of Arginase Are Not Components of Pathogenesis Mediated by Francisella Species

Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms. Pathogenicity of Francisella infections is tied to its unique ability to evade and suppress inflammatory responses in host cel...

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Main Authors: Griffin, Amanda J., Crane, Deborah D., Wehrly, Tara D., Scott, Dana P., Bosio, Catharine M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855703/
https://ncbi.nlm.nih.gov/pubmed/24324751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082096
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