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Structure and pH-Induced Structural Rearrangements of the Putative Multidrug Efflux Pump EmrD in Liposomes Probed by Site-directed Spin Labeling
EmrD is the only structurally characterized drug/H(+) antiporter of the major facilitator superfamily (MFS). It has been crystallized in a doubly-occluded conformation that is considered representative of an intermediate state in the transport cycle of MFS transporters. However, unexpected features...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855667/ https://ncbi.nlm.nih.gov/pubmed/24148002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4012385 |
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