Research on the Premotor Symptoms of Parkinson’s Disease: Clinical and Etiological Implications

Background: The etiology and natural history of Parkinson’s disease (PD) are not well understood. Some non-motor symptoms such as hyposmia, rapid eye movement sleep behavior disorder, and constipation may develop during the prodromal stage of PD and precede PD diagnosis by years. Objectives: We exam...

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Autori principali: Chen, Honglei, Burton, Edward A., Ross, G. Webster, Huang, Xuemei, Savica, Rodolfo, Abbott, Robert D., Ascherio, Alberto, Caviness, John N., Gao, Xiang, Gray, Kimberly A., Hong, Jau-Shyong, Kamel, Freya, Jennings, Danna, Kirshner, Annette, Lawler, Cindy, Liu, Rui, Miller, Gary W., Nussbaum, Robert, Peddada, Shyamal D., Rick, Amy Comstock, Ritz, Beate, Siderowf, Andrew D., Tanner, Caroline M., Tröster, Alexander I., Zhang, Jing
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2013
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Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855519/
https://ncbi.nlm.nih.gov/pubmed/23933572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1306967
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