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A Dose–Response Study of Arsenic Exposure and Global Methylation of Peripheral Blood Mononuclear Cell DNA in Bangladeshi Adults

Background: Several studies employing cell culture and animal models have suggested that arsenic (As) exposure induces global DNA hypomethylation. However, As has been associated with global DNA hypermethylation in human study populations. We hypothesized that this discrepancy may reflect a nonlinea...

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Detalhes bibliográficos
Main Authors: Niedzwiecki, Megan M., Hall, Megan N., Liu, Xinhua, Oka, Julie, Harper, Kristin N., Slavkovich, Vesna, Ilievski, Vesna, Levy, Diane, van Geen, Alexander, Mey, Jacob L., Alam, Shafiul, Siddique, Abu B., Parvez, Faruque, Graziano, Joseph H., Gamble, Mary V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855504/
https://ncbi.nlm.nih.gov/pubmed/24013868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1206421
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