Regulation of hepatic sulfotransferase (SULT) 1E1 expression and effects on estrogenic activity in cystic fibrosis (CF)()

Cystic fibrosis (CF) is a major genetic disease in Caucasians affecting 1 in 2500 newborns. Hepatobiliary pathology is a major cause of morbidity and mortality in CF second only to pulmonary disease. SULT1E1 activity is significantly elevated, generally 20–30-fold, in hepatocytes of mouse models of...

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Главные авторы: Falany, Charles N., He, Dongning, Li, Li, Falany, Josie L., Wilborn, Teresa W., Kocarek, Thomas A., Runge-Morris, Melissa
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855421/
https://ncbi.nlm.nih.gov/pubmed/19429440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2009.02.009
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