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The autophagy inhibitor chloroquine overcomes the innate resistance to erlotinib of non-small cell lung cancer cells with wild-type EGFR
INTRODUCTION: The EGFR inhibitor erlotinib is much less effective in NSCLC tumors with wild-type EGFR than in tumors with activating EGFR mutations. Autophagy is a tightly regulated lysosomal self-digestion process that may alternatively promote cell survival or type II cell death. This study assess...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855301/ https://ncbi.nlm.nih.gov/pubmed/23575415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31828c7210 |
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