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New roles opined for OPCML
OPCML, frequently inactivated in ovarian tumors, mediates its anti-tumor effect via binding to the extracellular domains of several important oncogenic receptor tyrosine kinases (RTKs). This, in turn, leads to the down-regulation of RTKs in tumor cells and results in significant inhibition of tumor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854967/ https://ncbi.nlm.nih.gov/pubmed/22585855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0356 |
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