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Optic Nerve Inflammation and Demyelination in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy

PURPOSE. Optic nerve (ON) ischemia associated with nonarteric anterior ischemic optic neuropathy (NAION) results in axon and myelin damage. Myelin damage activates the intraneural Ras homolog A (RhoA), contributing to axonal regeneration failure. We hypothesized that increasing extrinsic macrophage...

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Detalhes bibliográficos
Main Authors: Slater, Bernard J., Vilson, Fernandino L., Guo, Yan, Weinreich, Daniel, Hwang, Shelly, Bernstein, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854773/
https://ncbi.nlm.nih.gov/pubmed/24065807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12064
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