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Aldehyde dehydrogenase and ATP binding cassette transporter G2 (ABCG2) functional assays isolate different populations of prostate stem cells where ABCG2 function selects for cells with increased stem cell activity

INTRODUCTION: High expression of aldehyde dehydrogenase1A1 (ALDH1A1) is observed in many organs and tumors and may identify benign and cancer stem cell populations. METHODS: In the current study, the stem cell characteristics were determined in cells isolated from human prostate cell lines and clini...

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Detalhes bibliográficos
Main Authors: Gangavarapu, Kalyan J, Azabdaftari, Gissou, Morrison, Carl D, Miller, Austin, Foster, Barbara A, Huss, Wendy J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854760/
https://ncbi.nlm.nih.gov/pubmed/24405526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt343
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