Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model

INTRODUCTION: Cell therapy is a potential therapeutic approach for neurodegenerative disorders, such as Alzheimer disease (AD). Neuronal differentiation of stem cells before transplantation is a promising procedure for cell therapy. However, the therapeutic impact and mechanisms of action of neuron-...

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Detalhes bibliográficos
Main Authors: Yang, Hui, Xie, ZhaoHong, Wei, LiFei, Yang, HongNa, Yang, ShaoNan, Zhu, ZhengYu, Wang, Ping, Zhao, CuiPing, Bi, JianZhong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854736/
https://ncbi.nlm.nih.gov/pubmed/23826983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt227
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