Handling Uncertainty in Dynamic Models: The Pentose Phosphate Pathway in Trypanosoma brucei

Dynamic models of metabolism can be useful in identifying potential drug targets, especially in unicellular organisms. A model of glycolysis in the causative agent of human African trypanosomiasis, Trypanosoma brucei, has already shown the utility of this approach. Here we add the pentose phosphate...

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Hauptverfasser: Kerkhoven, Eduard J., Achcar, Fiona, Alibu, Vincent P., Burchmore, Richard J., Gilbert, Ian H., Trybiło, Maciej, Driessen, Nicole N., Gilbert, David, Breitling, Rainer, Bakker, Barbara M., Barrett, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854711/
https://ncbi.nlm.nih.gov/pubmed/24339766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003371
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