MicroRNA-21 promotes the ovarian teratocarcinoma PA1 cell line by sustaining cancer stem/progenitor populations in vitro

INTRODUCTION: Resistance of cancer stem/progenitor cells (CSPCs) to chemotherapy can lead to cancer relapse. Ovarian teratocarcinoma (OVTC) arises from germ cells and comprises pluripotent cells that can be used to study cancer cell stemness. In this study, we evaluated whether microRNA-21 (miR-21)...

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Huvudupphovsmän: Chung, Wei-Min, Chang, Wei-Chun, Chen, Lumin, Chang, Ying-Yi, Shyr, Chih-Rong, Hung, Yao-Ching, Ma, Wen-Lung
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854706/
https://ncbi.nlm.nih.gov/pubmed/23890123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt247
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