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Clearance of Apoptotic Cells by Macrophages Induces Regulatory Phenotype and Involves Stimulation of CD36 and Platelet-Activating Factor Receptor

Phagocytosis of apoptotic cells (efferocytosis) induces macrophage differentiation towards a regulatory phenotype (IL-10(high)/IL-12p40(low)). CD36 is involved in the recognition of apoptotic cells (AC), and we have shown that the platelet-activating factor receptor (PAFR) is also involved. Here, we...

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Autori principali: Ferracini, Matheus, Rios, Francisco J. O., Pecenin, Mateus, Jancar, Sonia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854564/
https://ncbi.nlm.nih.gov/pubmed/24347838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/950273
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