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Understanding Variation in Transcription Factor Binding by Modeling Transcription Factor Genome-Epigenome Interactions
Despite explosive growth in genomic datasets, the methods for studying epigenomic mechanisms of gene regulation remain primitive. Here we present a model-based approach to systematically analyze the epigenomic functions in modulating transcription factor-DNA binding. Based on the first principles of...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854512/ https://ncbi.nlm.nih.gov/pubmed/24339764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003367 |
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