Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer

Cisplatin resistance remains one of the major obstacles when treating epithelial ovarian cancer. Because oxaliplatin and nedaplatin are effective against cisplatin-resistant ovarian cancer in clinical trials and signal transducer and activator of transcription 3 (STAT3) is associated with cisplatin...

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Main Authors: Sheng, W.J., Jiang, H., Wu, D.L., Zheng, J.H.
Format: Artigo
Jezik:Inglês
Izdano: Associação Brasileira de Divulgação Científica 2013
Teme:
Biomedical Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854422/
https://ncbi.nlm.nih.gov/pubmed/23969971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20133003
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