Proteomic data show an increase in autoantibodies and alpha-fetoprotein and a decrease in apolipoprotein A-II with time in sera from senescence-accelerated mice

We evaluated changes in levels by comparing serum proteins in senescence-accelerated mouse-prone 8 (SAMP8) mice at 2, 6, 12, and 15 months of age (SAMP8-2 m, -6 m, -12 m, -15 m) to age-matched SAM-resistant 1 (SAMR1) mice. Mice were sacrificed, and blood was analyzed by 2-dimensional electrophoresis...

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Bibliographic Details
Main Authors: Guo, S.J., Qi, C.H., Zhou, W.X., Zhang, Y.X., Zhang, X.M., Wang, J., Wang, H.X.
Format: Artigo
Language:Inglês
Published: Associação Brasileira de Divulgação Científica 2013
Subjects:
Biomedical Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854399/
https://ncbi.nlm.nih.gov/pubmed/23588375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20132663
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