Kaurene diterpene induces apoptosis in U87 human malignant glioblastoma cells by suppression of anti-apoptotic signals and activation of cysteine proteases

Gliomas are the most common and malignant primary brain tumors in humans. Studies have shown that classes of kaurene diterpene have anti-tumor activity related to their ability to induce apoptosis. We investigated the response of the human glioblastoma cell line U87 to treatment with ent-kaur-16-en-...

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Autors principals: Lizarte, F.S., Tirapelli, D.P.C., Ambrosio, S.R., Tirapelli, C.R., Oliveira, F.M., Novais, P.C., Peria, F.M., Oliveira, H.F., Carlotti, C.G., Tirapelli, L.F.
Format: Artigo
Idioma:Inglês
Publicat: Associação Brasileira de Divulgação Científica 2013
Matèries:
Clinical Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854348/
https://ncbi.nlm.nih.gov/pubmed/23314342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20121423
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