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Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation

Lopap, found in the bristles of Lonomia obliqua caterpillar, is the first exogenous prothrombin activator that shows serine protease-like activity, independent of prothrombinase components and unique lipocalin reported to interfere with hemostasis mechanisms. To assess the action of an exogenous pro...

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Autors principals: Andrade, S.A., Carrijo-Carvalho, L.C., Peceguini, L.A.M., Wlian, L., Sato, A.C., Luchiari, C., Silva, E.D., Maffei, F.H.A., Chudzinski-Tavassi, A.M.
Format: Artigo
Idioma:Inglês
Publicat: Sociedade Brasileira de Medicina Tropical 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854179/
https://ncbi.nlm.nih.gov/pubmed/22735179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S0100-879X2012007500108
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