Antitumor efficacy of a recombinant adenovirus encoding endostatin combined with an E1B55KD-deficient adenovirus in gastric cancer cells

BACKGROUND: Gene therapy using a recombinant adenovirus (Ad) encoding secretory human endostatin (Ad-Endo) has been demonstrated to be a promising antiangiogenesis and antitumor strategy of in animal models and clinical trials. The E1B55KD-deficient Ad dl1520 was also found to replicate selectively...

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Autors principals: Li, Li-xia, Zhang, Yan-ling, Zhou, Ling, Ke, Miao-la, Chen, Jie-min, Fu, Xiang, Ye, Chun-ling, Wu, Jiang-xue, Liu, Ran-yi, Huang, Wenlin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853970/
https://ncbi.nlm.nih.gov/pubmed/24124726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-257
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