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Vismodegib: A smoothened inhibitor for the treatment of advanced basal cell carcinoma

Incidence of basal cell carcinoma (BCC), the most common skin cancer in humans, is rising. Surgery is the mainstay of treatment but there is no standard of care for locally advanced or metastatic disease. Hedgehog signaling proteins are critical for cell growth and differentiation during embryogenes...

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Bibliographic Details
Main Authors: Aditya, Suruchi, Rattan, Aditya
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853913/
https://ncbi.nlm.nih.gov/pubmed/24350028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2229-5178.120685
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