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Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense.

The renin-angiotensin system plays a crucial role in the development and establishment of the hypertensive state in the spontaneously hypertensive (SH) rat. Interruption of this system's activity by pharmacological means results in the lowering of blood pressure (BP) and control of hypertension. How...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Iyer, S N, Lu, D, Katovich, M J, Raizada, M K
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9960
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