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Genistein-induced G2/M cell cycle arrest of human intestinal colon cancer Caco-2 cells is associated with Cyclin B1 and Chk2 down-regulation

Genistein is an isoflavonic phyto-oestrogen contained in soya beans. It is thought to display anti-cancer effects. This study was designed to investigate its effect on human intestinal colon cancer Caco-2 cells. MTT assay, flow cytometric analysis and western blotting were used to investigate the ef...

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Autori principali: Han, Junkyu, Kurita, Yui, Isoda, Hiroko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853634/
https://ncbi.nlm.nih.gov/pubmed/23794041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9592-0
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