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α-Linolenic acid suppresses cholesterol and triacylglycerol biosynthesis pathway by suppressing SREBP-2, SREBP-1a and -1c expression

α-Linolenic acid (ALA), a major fatty acid in flaxseed oil, has multiple functionalities such as anti-cardiovascular and anti-hypertensive activities. In this study, we investigated the effects of ALA on lipid metabolism and studied the possible mechanisms of its action in differentiated 3T3-L1 adip...

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Detalhes bibliográficos
Main Authors: Fukumitsu, Satoshi, Villareal, Myra O., Onaga, Shoko, Aida, Kazuhiko, Han, Junkyu, Isoda, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853632/
https://ncbi.nlm.nih.gov/pubmed/23138267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-012-9510-x
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