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Early QT assessment – how can our confidence in the data be improved?

Exposure–response (ER) analysis has emerged as an important tool to interpret QT data from thorough QT (TQT) studies and allows the prediction of effects in the targeted patient population. Recently, ER analysis has also been applied to data from early clinical pharmacology studies, such as single a...

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Detalhes bibliográficos
Main Authors: Darpo, Borje, Garnett, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853524/
https://ncbi.nlm.nih.gov/pubmed/23278510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12068
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