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Progressive limb ataxia following inferior olive lesions

Cerebellar climbing fibres originate in the inferior olive (IO). Temporary IO inactivation produces movement deficits. Does permanent inactivation produce similar deficits and, if so, do they recover? The excitotoxin, kainic acid, was injected into the rostral IO of three cats. Behaviour was measure...

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Autori principali: Horn, K M, Deep, A, Gibson, A R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853490/
https://ncbi.nlm.nih.gov/pubmed/23027819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.234898
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