Integrating GWASs and Human Protein Interaction Networks Identifies a Gene Subnetwork Underlying Alcohol Dependence

Despite a significant genetic contribution to alcohol dependence (AD), few AD-risk genes have been identified to date. In the current study, we aimed to integrate genome-wide association studies (GWASs) and human protein interaction networks to investigate whether a subnetwork of genes whose protein...

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Autores principales: Han, Shizhong, Yang, Bao-Zhu, Kranzler, Henry R., Liu, Xiaoming, Zhao, Hongyu, Farrer, Lindsay A., Boerwinkle, Eric, Potash, James B., Gelernter, Joel
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853414/
https://ncbi.nlm.nih.gov/pubmed/24268660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.10.021
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