The pfmdr1 gene of Plasmodium falciparum confers cellular resistance to antimalarial drugs in yeast cells.

The exact role of the pfmdr1 gene in the emergence of drug resistance in the malarial parasite Plasmodium falciparum remains controversial. pfmdr1 is a member of the ATP binding cassette (ABC) superfamily of transporters that includes the mammalian P-glycoprotein family. We have introduced wild-type...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ruetz, S, Delling, U, Brault, M, Schurr, E, Gros, P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38534/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790436/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9942
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