Pseudotyping the adenovirus serotype 5 capsid with both the fibre and penton of serotype 35 enhances vascular smooth muscle cell transduction

Ex vivo gene therapy during coronary artery bypass grafting (CABG) holds great potential to prevent excessive smooth muscle cell (SMC) proliferation, neointima formation and graft failure. The most successful preclinical strategies to date have utilised vectors based on the species C adenovirus, Ad5...

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Detalhes bibliográficos
Main Authors: Parker, A L, White, K M, Lavery, C A, Custers, J, Waddington, S N, Baker, A H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853367/
https://ncbi.nlm.nih.gov/pubmed/24005577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.44
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