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Wild-Type and Mutant Hemagglutinin Fusion Peptides Alter Bilayer Structure as Well as Kinetics and Activation Thermodynamics of Stalk and Pore Formation Differently: Mechanistic Implications

Viral fusion peptides are short N-terminal regions of type-1 viral fusion proteins that are critical for virus entry. Although the importance of viral fusion peptides in virus-cell membrane fusion is established, little is known about how they function. We report the effects of wild-type (WT) hemagg...

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Detalhes bibliográficos
Main Authors: Chakraborty, Hirak, Tarafdar, Pradip K., Klapper, David G., Lentz, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853327/
https://ncbi.nlm.nih.gov/pubmed/24314080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.010
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