12/15-Lipoxygenase Contributes to Platelet-derived Growth Factor-induced Activation of Signal Transducer and Activator of Transcription 3

We showed previously that the small molecule indirubin-3′-monoxime (I3MO) prevents vascular smooth muscle cell (VSMC) proliferation by selectively inhibiting signal transducer and activator of transcription 3 (STAT3). Looking for the underlying upstream molecular mechanism, we here reveal the import...

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Detalhes bibliográficos
Main Authors: Blažević, Tina, Schwaiberger, Andrea V., Schreiner, Cornelia E., Schachner, Daniel, Schaible, Anja M., Grojer, Christoph S., Atanasov, Atanas G., Werz, Oliver, Dirsch, Verena M., Heiss, Elke H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853304/
https://ncbi.nlm.nih.gov/pubmed/24165129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.489013
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